Delsin Rowe from inFAMOUS: Second Son vs. Alex Mercer from Prototype. Battle is set in New York City, Alex's home. Opponents will fight until the death. Keep in mind each opponent's powers, strengths, and weaknesses.
Post your opinions in the comments section and provide backup. (Example: Don't just say "Alex will win because Delsin sucks" or whatever. Provide evidence, such as "Times Square may do Delsin good with all the neon and video.) And don't add unnecessary things, like Cole MacGrath or James Heller, this is between Delsin and Alex ONLY.
Now don't hold back; post ya heart out!