inFamous: Second Son
- “Now, I gotta go back to my office...apparently I'm getting a phone call.”
- — Betty, after telling Delsin she is helping him for the last time.
Betty heard a noise and comes out of her office, armed with a stapler, only to find Delsin, who jumped in from the roof after tagging his brother's Sheriff billboard. When they hear Reggie demanding Betty to open the door, she lets Delsin use the back door to get out so he can try to get to the Longhouse, which fails leading to Delsin's arrest by Reggie. Later, her warehouse is set on fire by Bioterrorist Hank Daughtry, who escaped from the DUP, to create a distraction and tries telling her to get out, but refuses to listen to him. Upon seeing smoke come out of Delsin's finger, she runs away only to get caught by Brooke Augustine. She soon watched in horror as Augustine stabs Delsin with her Concrete powers before he either confesses to being a conduit or curses her, causing Augustine to stab Betty in the leg before they leave them for dead.
Later, when Delsin wakes up and finds Betty, she either prases him for trying to save the tribe, or scolds him. Betty calls at certain points in the story, such as when Delsin is crossing the 520 bridge, only to end the conversation shortly after. When he is scaling the Seattle Space Needle, depending on his Karma, Delsin either says that he is at the space needle and Betty asks for him to "bring [her] a postcard" (Good Karma), or truthfully states that he is "kinda climbing up the outside of the Space Needle", to which she humorously replies "Well, if you don't want to talk to me, just say so", unaware of the fact that Delsin is acually going up the Space Needle (Evil Karma).
Betty wakes up to see Delsin healing her leg by removing the concrete spikes off her with his own concrete powers he absorbed from Augustine and asks about Reggie, but Delsin doesn't answer. He did mention to her that his brother saved his life.
Betty comes up to Delsin, in a wheelchair, disappointed and actin all cray because of Delsin becoming evil and tells him he is no longer part of the Akomish tribe, before slamming the door in front of him. Delsin soon performs an Orbital Drop, presumably destroying the Longhouse and killing Betty.
- Her role in the game serves a similar purpose to Wolfe from InFamous 2, as being a mentor-like character that's mostly seen off-screen.