The Staton Building is a location in Infamous.
In the first level where Cole wakes up after the The Blast, you can clearly see the building. The police tell him to make his way past the building and through the parking lot to the bridge connecting the Historic District and Neon District.
Also, in the final level, Kessler tells Cole to meet him in front of the Staton Building.
In the evil ending, Cole is shown to be narrating the conclusion of the game while overlooking a destroyed Empire City from the Staton Building.